World's Most Giant Doctor is a character that J.D. and Turk like to act out in their free time. One stands on the other's shoulders and talks in a loud voice. Usually J.D. is on the top, but occasionally they will do World's Most Giant Black Doctor with Turk on the top, but this occasionally scares people away from the hospital.
- “Hello, citizens! Welcome to Sacred Heart! Home of the world's most giant doctor! Be not afraid! I'm just like you! Except I'm giant!”— J.D. ("My Clean Break")
- “All right! My turn to get on top!”— Turk
- “Turk, we tried playing Giant Black Guy. Remember what happened? People ran.”— J.D. ("My Clean Break")
- “Good morning, Dr. Cox! From the world's most giant doctor!”— J.D. ("My Ocardial Infarction")
- “And if any of you cows, goats, or ducks have any questions, don't be afraid to ask me! I'm just like all of you, only giant and human!”— J.D.
[The audience laughs.]
- “Thank you. I hope you enjoyed our production of World's Most Giant Doctor Goes to the Farm.” ("My Life in Four Cameras")