- “I, uh, I think what she means is, she doesn't give a crappuccino!”— Dr. Kelso
"My Drug Buddy" is the fourteenth episode of Scrubs' first season. J.D. and Alex keep getting interrupted before they can have sex. Turk keeps on meeting Dr. Cox at the toilet, and they get to know each other. Dr. Kelso gives Carla several rides to work, and they temporarily become friends.
J.D. is enamored with his new girlfriend, Alex, but they haven't had sex yet. Alex says she is ready, but first Turk and later Elliot interrupt just as J.D. and Alex start to get passionate. Dr. Kelso and Carla become friends while he drives her to work, which causes the other nurses to be upset with Carla. At Carla's behest, Turk tries to become friends with Dr. Cox, and they wind up on the same pee schedule. After some Percocet goes missing, Elliot accuses a recovering addict patient, while Alex defends him, putting J.D. in the middle. J.D. accuses Elliot of being jealous and tells her she had a chance with him, but she blew it. Elliot is hurt, even shouldering him at work.
In the end, Carla discovers that Dr. Kelso does what makes him happy and doesn't care what other people think, and this hits home when he drives through a puddle, splashing her rather than picking her up. Dr. Cox and Turk come to an understanding about Dr. Cox's crush on Carla. J.D. learns that Alex is the true drug thief, and when he apologizes to Elliot for accusing her of being jealous, she admits she was jealous. She then advances on him and they make out, proceeding to the bed to have sex.
- A marching band, including a monkey slamming cymbals together, enters J.D.'s bedroom after Alex says she's ready to have sex with him. The monkey covers its eyes before the cut to the title.
- Elliot sprays J.D. and Alex with a fire hose in the on-call room as they were about to have sex.
- J.D. arranges flowers on the bed for when he and Alex have sex.
Janitor bets J.D. $20 that he won't get to sleep with Alex. J.D. originally refuses to comment on the matter and deems it personal. Somehow, Janitor claims to know they did not sleep together and wins the bet.
J.D.'s girl names
- Grace (two times)
- Dr. Cox also calls Elliot "Will"; therefore, she and J.D. are Will and Grace.
- “All right, Will and Grace, break down.”— Dr. Cox
- “Okay, Grace, you want to finish?”— Dr. Cox
- Elizabeth Bogush as Alex Hanson
- Jim Blanchette as Allan
- Brian Catalano as Yuppie
- Al Harrington as Mr. Barnes
- Lynne Maclean as Nurse Kearney
- "Fighting For My Love" by Nil Lara
- "1812 Overture (Opus 49)" by Pyotr Ilyich Tchaikovsky
- “Oh, for the love of Oprah!”— Dr. Cox
- “I yelled at you because that paperwork looked like it had been done by a drunk four-year-old.”— Dr. Kelso
- Dr. Cox learns Turk's name in this episode.
- Elliot suspects an addict of stealing drugs in this episode, but in "My Scrubs", she is more forgiving and does not believe that Sam Thompson is conning people into giving him drugs, even though he nearly conned her in the past. However, this could be explained by Elliot's desire to disagree with Alex because of her jealousy over J.D.
- In the scene where Carla misses the bus and asks Dr. Kelso for a ride, there is obviously no traffic in the street, so Dr. Kelso has not been delayed by the bus, and his car is parked. He has no reason whatsoever to be there, as he doesn't live in the neighborhood, and just passes the street when he splashes water on Carla.
- When the Janitor says "He didn't sleep with her" while Elliot and J.D. are talking in the cafeteria, Elliot doesn't acknowledge his response. This is in line with the idea of him being in J.D.'s imagination.
- J.D. takes the drugs out of Alex's purse twice, but only reacts the second time.
- When J.D. says to Alex, "Remember when the new Star Wars movie came out and it was built up, and people went to see it, but it really wasn't that great in bed?", he is referring to Star Wars Episode I: The Phantom Menace, released 16 years after the last Star Wars movie.
- When Laverne says, "I was supposed to see my nephew tonight in Pippin", she is referring to the stage musical Pippin.
- When Dr. Cox says "Oh, for the love of Oprah!", he is referring to Oprah Winfrey, the host of The Oprah Winfrey Show.
- J.D. calling Janitor "Jolly Green" is an allusion to the Green Giant food company's symbol, the Jolly Green Giant.
- Dr. Cox calls J.D. and Elliot "Will and Grace", an allusion to the NBC sitcom Will and Grace, which is focused on the lives of Will Truman, a gay lawyer, and his best friend, Grace Adler, a straight Jewish woman.
- "My Drug Buddy" is a song by The Lemonheads on the album It's a Shame About Ray.
- The treatment record held by the nurse talking to Laverne about her nephew is a military medical record.
- Title explanation: J.D.'s new girlfriend, Alex, is a drug addict.