Scrubs was Liliana's first acting role. Since then, she has appeared in the TV series That '70s Show, My Wife and Kids, Lilo & Stitch: The Series, and Higglytown Heroes. She has appeared in the films The Santa Clause 2 and 3, Lilo & Stitch 2, Barnyard, and most notably Cheaper by the Dozen and Cheaper by the Dozen 2. Liliana has been nominated 3 times and won once, for a Young Artist Award. She also is currently known for playing Panini, on the Cartoon Network original series, Chowder, playing the "girlfriend" of the main character, Chowder.