In one scene of the movie, Miss Piggy has quit the Muppet theater and is now working on Scrubs. However, she is not a star, nor even a guest star. She is an extra playing a dead body. In the scene, the Scrubs staff, including J.D., Dr. Cox, Elliot, and Carla attempt resuscitating a patient using a defibrillator. After Dr. Cox declares the patient dead, the "patient" sits up and complains that the show is not using her abilities to their fullest. She tries to convince Bill Lawrence that she should play a sexy nurse with attitude, and hints that Carla would have to leave the show. She also throws out the idea that she could play a woman janitor, but that "Frankenstein" (Janitor) would have to be cut as well.
When Kermit the Frog attempts to convince Miss Piggy to come back and act on their show, rather than Scrubs, she tells him that she doesn't want to leave. Bill Lawrence then fires her and the actors tell her she needs to leave. Eventually she decides that she quits, and leaves with Kermit.
- Zach Braff as Himself/J.D.
- Sarah Chalke as Herself/Elliot Reid
- Neil Flynn as Himself/Janitor
- John C. McGinley as Himself/Perry Cox
- Bill Lawrence as Himself
- Judy Reyes as Herself/Carla Espinosa
- It's a Very Muppet Christmas Movie at the Muppet Wikia